Translational Cancer Research Program
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چکیده
Tumor microenvironment regulates cancer cell survival, metastasis, inflammation, and immune surveillance. There is growing evidence that the lymph node (LN) microenvironment, especially lymph node stromal cells (LNSCs), play a significant role in solid tumor growth, drug resistance, and subsequent extra-nodal metastasis of many types of cancer. A comprehensive understanding of the associated molecular mechanisms and pathways that are involved in tumor progression and metastasis would have substantial benefits for high-risk cancer patients.
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Laboratory of Molecular and Cellular Aging, Institute of Biological Research and Biotechnology, National Hellenic Research Foundation; Faculty of Biology, Department of Cell Biology and Biophysics, University of Athens, Athens, Greece; Immunology Program, H. Lee Moffitt Cancer Center, Tampa, Florida; and Departments of Oncology and Pharmacology, Program in Cell Stress and Cancer Nanomedicine, L...
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